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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b3f12f6b009b9116aabe0030449f58ce00443079bc550912344f9b9483cddd' 
  AND token = 'ZVkFHT9+RBLlUN93Moc45jAgs9k/kDDn4fHX9C1MDzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}