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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d993e48b19937efc1f7aa2129aec78e54fa77512635baaad466a7ae9261d5c' 
  AND token = 'nk/iRjb4pMCf3vhP5T/bZd0n5+0RCJ0ILu76YB5nuYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}