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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4afca5ae7d5c873b7bd8d6e5fb95bc6914f95524e1ffde136b64bb6bfc70e767' 
  AND token = '2uiXa2wUEBc9CyVclox0sw7ZjgkYd9zjSKlENZcAw9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}