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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817bee59e16a8f19956cef0025f9dc069097761d4c073d06c4d97e5c5dc67eb7' 
  AND token = 'IwCS4MU25NsqlDD51XvmjPGUATGGyOJqbk6L1wjHPPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}