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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b29e88fbf6e56ee95b5548ef79587549c1e055621067a4c679490f0a558c1fc' 
  AND token = '8N4Byna+/IwENkKes/gXLtaNU3swvlxbgRMd9UOyLl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}