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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7877916578a746836a878c99207423c7e6623a290948980723836b0e4baec3e5' 
  AND token = 'GT7o2aW6VWC0jRflBVB3c+prTXBNTjqVp7DecTgppCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}