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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b50f7a3e50248f4b9059445cfb9052a3ecc7edf8f9c5ff4f265437ba844a88c' 
  AND token = '9/9s3NOlB/ts4nX1fNh09H4ll2MlUJqHLv6FRq0pHOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}