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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e15f8367d70d6999a58ce7a11ff4694d71bea48faab9489fb3a3bc5bedf50ce7' 
  AND token = 'aDei2j6rcEw7EI1tYQNELF6dpNjOaMM0ZZjuyck62dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}