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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d5597434979ea32ffcbac4c6914cea85410af5b2aafd297d5a8e585f44648ef' 
  AND token = 'yH2ij0MmF50Iz/0yk15Kn8lbzzoTl9Wh9pm1EsL/Yro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}