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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f14f2f58d0e5acea11645afb50fa4d4e3714e7f2742fb5eaa64bf720a6b1c97' 
  AND token = 'uIS1C+oBDtZBJofEVWdnQpvCD22s/mI3hGuqJ0i0qQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}