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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6921f0474bec775ade659b0665b3153578801aa7cc6b0948dfa89e9f97e275a2' 
  AND token = 'E3yQ4yLFP4w7AKe+28wA1yaRrnqJ8xCeOVa36t1Kz1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}