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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3cfa564733962e32289d999e79ca7fe367b01c33dec3b1ba5705cd89084c397' 
  AND token = '65Uq7k/gPBOu4qxDv1qzRMhLwB4TQXeydFEQqhyEUjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}