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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee91db341553786e4b824ddb27a13178403d033f3255fe4ae3d0825d79e44246' 
  AND token = 'BnaSmcrxS+C6DBHyx7WFec/340HzqbXAWJqRvMRB1vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}