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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd285dfedf34465caffc596b2d2b00472a2b6b2c0ffe80c43f52e37e4e3e346d6' 
  AND token = 'qiI47YiC5SrNCTeXpdc5A3RslKbpW4ZE7XZz+lLhhgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}