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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3ab2dfc1d2001e21115496d24d314d9aec42d600b9e0c39a2b708de3792221' 
  AND token = 'qzMyIAzHTkKWK0E7Yq8P21CKsNRsosJkcpqyTjQGVUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}