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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5858b3b15bbc24f36d4a522c390746c3df116dd456e6c26bd4b829e5b489c16' 
  AND token = 'Uzcv1si9807DxAg46eNpdiqoGJNZr08H+vzi92620lU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}