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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a32541f8105e378f5077c42aafaf62f90defb38e2b710e3fd78885f57e6f0a7' 
  AND token = 'nj5mlTFkk2/LWp/3cNS4rqyBxtKaA3HhG/mSZxdpYzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}