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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b3dddb463e962a44632fcfcf4820f02933d2f6dcfafc3e1e008af206fa810b' 
  AND token = 'dIpfC0LRB7aGAQ58uf6H6rriyrFL+f09zzOECW6LNrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}