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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a40ba01da6cc394a06aea0cbe8bab53d06f5e19b36f8c47914df87290326d1b' 
  AND token = 'vIpOT0qLqV450nOQuElK1OjrcF6ZLLM5RKoXMb+WNzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}