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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '681f0f6616847d9b3b4f6dae9e743f4bdb84cd13e58f51f31e5a7ca63cc0ce65' 
  AND token = '5qTqKKmKXqxazxriWjmiYYo/8V1Y8PzALdaTOH7HpAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}