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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e7f5a9d6084893ff503da228507901652dd037a4c9d794f9f973db131ad2468' 
  AND token = '/Yl2C7qOwQrUboSlFpMtz6K4VDUe4OfNgFtteA4YdFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}