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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8da0c358a2f4f68289a65fc16ca0c014065450ec65855c950b03b90666e450a5' 
  AND token = '2raEsKCz1GSbPJ1/3PdnCp0x2E+g5D5+aitjYKedRcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}