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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee5ec74982b94cc88b94beedf7037de77f850e76bf2e86763080ba295033c758' 
  AND token = 'EeYe2ewA3szl/NI4e+98S7lSHF8jq//A+2AeZfg1XZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}