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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd28a71f5546e520275e3ef0f7e216e7955b5c07b5ad610913564c57f27486620' 
  AND token = 'c6TeLecU+SpEnvDujCqDQQYE/9Is4ZFV0+PMgQx2dtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}