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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e8ebfc5f4e3734406e4707588afba5091dbf117178a41dd221fa295e6398bf' 
  AND token = 'DwHBYcwff1Tg9dBhnMKRNQH6V4l9JdKH2a/dI2Yx00o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}