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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cadd49f7ddd6ea0c5ad28c2294f66c6c9d7729d6619421f74475a8c868c489e7' 
  AND token = '11NW9mz1bsJ4oowSBQfID0utEWvt01XE9URwp84oijc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}