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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef791d2bfadc2012259921de794100d5d575b01d33c3edcfda2c264f08701a0' 
  AND token = 'wqk6wdz7K1KPML8pNNgRFV+6X6iwN0Uz/Fp2sfLgPIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}