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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bedd9797ed759f51bef9b8f0bfa0fef2619d0dc42f97cf327595bd779dd2c16' 
  AND token = 'pLCukSW9PnnUQG3mBI4zTtt4F9f1+jmPddLS69F48aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}