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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ef335e4bf8606902a2084ba73d41cb9c505d37b8a65fed7163d608d549d6bc' 
  AND token = 'PpSPHVpegDW16xiUVF3m2XMBUYSsf3j6XORSZQpyDew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}