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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f9239e4c8c25c72dd81df41d5c144bc037c227831e1be6ea66d9f3ad3fe0a4f' 
  AND token = 'IjhRm/TNFGrkA6z8nu5sSDObsJR3jDIfAiSzpmiPhAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}