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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '834b7399681ce62d1ac666ce71a1d940cad2a4a9ab01460d5a82136d4021fddc' 
  AND token = '2nDJma6xOvAMwbV+wiQPcecw2dy2NmzG/cko8qkZ5BQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}