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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fd1b35714b21f6c7086a6680db4e052f001bb4498564e909aeaa555039a7b35' 
  AND token = 'g8eYnFEV7wiH82lLdOzJ2GW16p36E4vxFjhgkMZGoV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}