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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fe9f2e7680cade5660e00ca2059b631bd3384b4c87168567e438ef5c19366ef' 
  AND token = '2CYfdIzLv1ijkmq/21+t6R0r96LBWcj93s+5SlFy3fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}