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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8551e8af48168e496c21ae44d6102705dd13fb4478475e65a751c923bcacbf' 
  AND token = 'PMYGaFq+/dwHmMQ+Mi7X5PmncG0Qw9PTS5BaaZRiuj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}