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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a245a54e5d3320165724caff7e727565eb7085b4fe7f3189a2ebe19ed2092787' 
  AND token = 'etHSCTes4n7M/BsF8+RRfm0NWbHTKHEmNLtlijmO740=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}