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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0a0b5857a4c0d9ccd6caa4fbce11e4b1aaf23805509b98248a0687829a82ff5' 
  AND token = 'laPyCE5j9toSArZk9hwcn+fk4CDZTWLWtFDEXb2ZtR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}