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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6afe5ce6c6d1f13429b2100a7fe528c847c5dcb45ed2fb56c39376514a2b25b' 
  AND token = 'QvBNwGPDbAS4bi7otMI9525qcJK2giTI+FIqQP/DlXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}