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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8bf325c3b6f4e30f7a23328efe4d1c00f837687a4a621ae8431026f0dd5ff42' 
  AND token = 'jnKC8WAAZMsbQYqDNIG+CnITt+ZAowVxp4CHQ50G0UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}