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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44523f5eeb8436a0920253d19cc1e3f7e5e78816ebbd8fcd8ebe6f0107842e27' 
  AND token = 'TvQp4JoK4YxW6iWAX/qwnLwC/9LH7UT8IN9Aqa0avBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}