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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5a9c8cc5bcd538db17750b62810720552eee2ab02335582e449ec4d72080621' 
  AND token = 'f2vUqfqoFCqJjOsxEZtwN6+Xd+vTvIPU/9sVc8ugoa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}