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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb3f70cca7e8e3e0f1edc6e380cbce2d28178d77b05781b8e85f5da51dfd3084' 
  AND token = 'EP/1TxifqBHXbbnOY7EZyl6AWjsSSF2HQMCTzOtIjR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}