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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d4fed23a2f7610cccfd897646d0c78972bb047f1006feaa35d589f8597d3646' 
  AND token = 'B4Q+FdvntFUkslI0qug9KRQWzoMlpTQR3T4+t0Xnrqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}