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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07e6cca66e4a7db6bf4ff5c88c5c6c1fcf87fd8d5920c2d9390a67be8e7506af' 
  AND token = '/GB9Ma9kNh8CvB9L6xJnkfNlxFjW0O1opg1+ZwUavcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}