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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6269222bd1e3e31fb4cbf31bce43670a590a821f14a30ac494695f349366029' 
  AND token = 'D3wKrCVJbbljvR2TFe6iOWUT23y/jSSt23i3NjZMBmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}