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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e27029208700150dbfe9c3003d03bf5eeac62041e4aaf38963a07c7e8fc5fe8' 
  AND token = 'Lo9w2W9O3n4icwQ/r6BeTRPiLZHBq7efz1JA7mljpx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}