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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8762384f492a49c122214934054663a07ff595bb9bae2419db918829ba67e74' 
  AND token = 'JYaF9qOuBUqEBup6KVcq41PcYFuB7pMxKPyPWIC2nIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}