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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645b79cb6e61d2e373e38e3ee11988aa6a47f760ecc61717cf3f399de30729e3' 
  AND token = 'rEfCFSDyKU4G8R8c1fV2OqywGMWO5bHeHmfCX4Vh0Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}