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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e0c7f7877248c18b55dfb5d0071192f223141d7b218b74457f30249185b003' 
  AND token = 'ANfPBusE9n2s1s/ANEJ3MCXAqwEdiKY4/CWpOJ1ZIKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}