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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da7a6a864a571969555a3303c093f63e078621008c2fffd332ca1b4c3845facc' 
  AND token = 'MmDDTn7m53Yp3TlA50AVGpYKdBNrchtsPwDU5XwndpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}