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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '140484789b1a1baad373b126813d967bc50c412a0520ef3351c69e84c40f1624' 
  AND token = '+4ePf1/662EVCMH9wY0B0eNMlmXG2jzLvuCBGm9fepU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}